See how to give a SYMJEPI injection in this short video. If you prefer written instructions, illustrated steps can be found just below the video player.
Keep in mind: Instructions for giving an injection with either SYMJEPI 0.3 mg or SYMJEPI 0.15 mg are exactly the same, so you only need to remember one set of steps.
When ready to use SYMJEPI, pull cap off to expose needle.
To ensure epinephrine does not leak by accident, do not touch the plunger until the needle is fully inserted.
While in a seated position, hold the device by the finger grips. Face the needle downward and slowly insert into the thigh.
SYMJEPI can be injected through clothing if necessary.
After needle is in the thigh, push the plunger all
the way down until it clicks. Hold for 2 seconds. Remove syringe and massage the area for 10 seconds.
The correct dose has been injected if the plunger has been pushed all the way down and the solution window is at least partially blocked.
Once the injection has been given, use one hand—with your fingers behind the needle—to slide the safety guard up until it clicks to cover the needle.
You may need a second SYMJEPI injection if symptoms continue or recur. More than 2 doses in a row should only be administered under direct medical supervision.
IMPORTANT NOTE: SYMJEPI should ONLY be injected into the middle of the outer thigh. Do not inject into the vein, buttock, fingers, toes, hands, or feet. If an accident happens and you inject SYMJEPI into another part of your or your child’s body, seek medical attention immediately.
Be aware Children can squirm in these stressful situations. During the SYMJEPI injection, hold your child’s leg firmly in place and limit his or her movement. This will reduce the risk of an injection-related injury.
Be safe SYMJEPI features a safety guard to keep you protected. Don’t forget to slide it up to cover the needle before putting the used SYMJEPI device back in its case.
Get helpSeek medical attention immediately after using SYMJEPI. You may need further medical attention and may need to use the second device if symptoms continue.*
Only a healthcare provider should give additional doses of epinephrine if you need more than 2 injections for a single anaphylaxis episode.
The best defense against anaphylaxis is to avoid what you are allergic to altogether. However, that may not always be possible, so creating an Anaphylaxis Action Plan and staying organized is the best way to prepare for a potential emergency.
SYMJEPI is indicated in the emergency treatment of allergic reactions (Type 1) including anaphylaxis to stinging insects (e.g., order Hymenoptera, which include bees, wasps, hornets, yellow jackets and fire ants) and biting insects (e.g., triatoma, mosquitoes), allergen immunotherapy, foods, drugs, diagnostic testing substances (e.g., radiocontrast media) and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis.
Contraindications
None.
Warnings and Precautions
Adverse Reactions
SYMJEPI may cause serious side effects.
Common side effects of SYMJEPI include:
These side effects may go away with rest. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of SYMJEPI. For more information, ask your healthcare provider or pharmacist.
Drug Interactions
Please see full Prescribing Information for SYMJEPI.
To report SUSPECTED ADVERSE REACTIONS, contact Adamis Pharmaceuticals Corporation at
Warnings and Precautions